Enriched blood IgG sialylation attenuates IgG-mediated and IgG-controlled-IgE-mediated allergic reactions
نویسندگان
چکیده
منابع مشابه
IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis.
Anti-neutrophil cytoplasmic autoantibodies (ANCA) directed against myeloperoxidase (MPO) and proteinase 3 (Pr3) are considered pathogenic in ANCA-associated necrotizing and crescentic glomerulonephritis (NCGN) and vasculitis. Modulation of ANCA IgG glycosylation may potentially reduce its pathogenicity by abolishing Fc receptor-mediated activation of leukocytes and complement. Here, we investig...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2021
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2020.05.056